Pursuing the middleman

نویسنده

  • Kendall Powell
چکیده

JCB • VOLUME 171 • NUMBER 4 • 2005 584 Pursuing the middleman: the hunt for integrins y the mid-1970s, the idea of a transmembrane molecule linking the cytoskeleton to the extracellular matrix (ECM) had some supporting evidence. Adhesion molecules were hot in areas ranging from developmental biology to tumor biology, and the mounting suggestive evidence that a “fibronectin receptor” existed made it a “Holy Grail” for the next decade, recalls Richard Hynes, discoverer of fibronectin, in a memoir (Hynes, 2004).

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عنوان ژورنال:
  • The Journal of Cell Biology

دوره 171  شماره 

صفحات  -

تاریخ انتشار 2005